Quinacrine-induced pathologic changes in the fallopian tube.
نویسندگان
چکیده
Sterilization has become the single most prevalent method of family planning on an international scale. It is estimated that approximately 80 million surgical sterilization procedures have been performed since the early 195Os, and the majority of these have been female.’ The demand for female sterilization is growing, and there is a clear need for a safe and effective nonsurgical method to terminate fertility. A transcervical chemical method is most desirable as it eliminates the need for surgery and thus could be a major contribution to family planning programs. For the past decade, Zipper and associates have been exploring the use of intrauterine quinacrine, a sclerosing agent, for the tubal ostia. Early experiments using multiple instillations of a quinacrine solution produced an unacceptably high pregnancy rate until the three instillations were completed. Recently, Zipper et al. have employed quinacrine pellets delivered through a modified intrauterine device (IUD) inserter. By compacting
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عنوان ژورنال:
- Fertility and sterility
دوره 33 6 شماره
صفحات -
تاریخ انتشار 1980